Impairment of thyroid function affects about 2% of adult women and about 0.1% to 0.2% of adult men in North America.
As many as 25% of patients with hypothyroidism have normal levels of T3.
Hypothyroidism can be associated with depression and its symptoms:
Even mild thyroid failure can have harmful effects.
Hypothyroidism occurs when there is an inadequate secretion of thyroid hormones, resulting in a slowing down of the body's metabolism. While low production of these hormones results in hypothyroidism, (an underactive thyroid) high production of these hormones results in hyperthyroidism, (an overactive thyroid).
Hyperthyroidism can be associated with:
· weight loss
· decreased menstrual flow
· vision changes
· lab tests will show: low TSH and high free T4.
Thyroid Disease in Pregnancy
Maternal thyroid disease is associated with adverse pregnancy outcomes and may negatively impact a child's neurocognitive development; for these reasons, the ATA stresses, screening is particularly important in women of childbearing age.
A mild, transient hyperthyroidism of pregnancy can occur during the first trimester, as increasing levels of human gonadotropin stimulate the thyroid. However, true hyperthyroidism during pregnancy is dangerous for both the woman and her fetus. The relative risk of prematurity can increase 16 times if hyperthyroidism isn't controlled. There is a ninefold increase in the risk of low birth weight and a fivefold increase in the risk of severe preeclampsia in these patients.
Postpartum thyroiditis will occur in 10% of women. The transient hyperthyroidism usually clears within 6-8 weeks, but transient hypothyroidism may follow and last up to 6 months. Beta-blockers can manage the hyper-metabolic symptoms. During the hypothyroid phase, thyroid hormone should be administered.
The goals of thyroid hormone replacement therapy are to normalize thyroid hormone levels and to provide symptomatic relief. Although there are several types of thyroid hormone replacement available, not any one type is optimal therapy for everyone. As a result, treatment options may vary from person to person.
Hypothyroidism is traditionally treated with thyroid hormone replacement therapy (either synthetic or natural). Thyroid replacement therapy could include taking levothyroxine (T4), liothyronine (T3), or a combination product that contains both T4 and T3. All of these treatments work in the body like thyroxine, the human hormone that is normally produced by the thyroid gland, and subsequently converted to T3, the active hormone.
Armour Thyroid is the leading combination therapy (T4/T3 ) product available for the treatment of hypothyroidism. It is a natural preparation derived from porcine thyroid glands.
Levothroid is a synthetic treatment containing the hormone levothyroxine (T4). It is both gluten-free and lactose-free. It treats hypothyroidism by replacing or supplementing the T4 that is normally produced by the thyroid.
Thyrolar is the only synthetic product combining L-triiodothyronine (T3) and levothyroxine sodium (T4 ) indicated for the treatment of hypothyroidism. This product is for patients who seek combination therapy in a synthetic form.
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